Restoration of skeletal muscle ischemia-reperfusion injury in humanized immunodeficient mice

BACKGROUND: Ischemia and reperfusion (I/R) of tissue provokes an inflammatory process that is highly dependent on circulating natural immunoglobulin M (IgM) and the complement cascade. In mice, a single IgM specificity produced by peritoneal B cells can initiate reperfusion injury. It is unknown whe...

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Bibliografiske detaljer
Main Authors: Sheu, Eric G., Oakes, Sean M., Ahmadi-Yazdi, Cyrus, Afnan, Jalil, Carroll, Michael C., Moore, Francis D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767199/
https://ncbi.nlm.nih.gov/pubmed/19628094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.06.010
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