A carregar...
MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis
Mixed-lineage kinase domain-like protein (MLKL) is essential for TNF-α–induced necroptosis. How MLKL promotes cell death is still under debate. Here we report that MLKL forms SDS-resistant, disulfide bond-dependent polymers during necroptosis in both human and mouse cells. MLKL polymers are independ...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5594682/ https://ncbi.nlm.nih.gov/pubmed/28827318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707531114 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|