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The 4E-BP growth pathway regulates the effect of ambient temperature on Drosophila metabolism and lifespan

Changes in body temperature can profoundly affect survival. The dramatic longevity-enhancing effect of cold has long been known in organisms ranging from invertebrates to mammals, yet the underlying mechanisms have only recently begun to be uncovered. In the nematode Caenorhabditis elegans, this pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Carvalho, Gil B., Drago, Ilaria, Hoxha, Sany, Yamada, Ryuichi, Mahneva, Olena, Bruce, Kimberley D., Soto Obando, Alina, Conti, Bruno, Ja, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594637/
https://ncbi.nlm.nih.gov/pubmed/28827349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618994114
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