The 4E-BP growth pathway regulates the effect of ambient temperature on Drosophila metabolism and lifespan

Changes in body temperature can profoundly affect survival. The dramatic longevity-enhancing effect of cold has long been known in organisms ranging from invertebrates to mammals, yet the underlying mechanisms have only recently begun to be uncovered. In the nematode Caenorhabditis elegans, this pro...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Carvalho, Gil B., Drago, Ilaria, Hoxha, Sany, Yamada, Ryuichi, Mahneva, Olena, Bruce, Kimberley D., Soto Obando, Alina, Conti, Bruno, Ja, William W.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594637/
https://ncbi.nlm.nih.gov/pubmed/28827349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618994114
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