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Interplay between H6PDH and 11β-HSD1 implicated in the pathogenesis of type 2 diabetes mellitus

Extensive studies have been performed on the role of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) in metabolic diseases. Our previous study reported glucose could directly regulate hexose-6-phosphate dehydrogenase (H6PDH) and 11β-HSD1. Recently, we further investigated the interplay of H6PDH and 11...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Yao, Fan, Chen, Li, Fan, Zheng, Teng, Fei, Zhao, Yali, Guan, Fengying, Zhang, Ming, Liu, Yanjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594562/
https://ncbi.nlm.nih.gov/pubmed/28751144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.07.043
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