Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination

Tumor immune escape is a critical problem which frequently accounts for the failure of therapeutic tumor vaccines. Among the most potent suppressors of tumor immunity are myeloid derived suppressor cells (MDSCs). MDSCs can be targeted by all-trans-retinoic-acid (atRA), which reduced their numbers an...

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Bibliografiska uppgifter
I publikationen:Oncoimmunology
Huvudupphovsmän: Heine, Annkristin, Flores, Chrystel, Gevensleben, Heidrun, Diehl, Linda, Heikenwalder, Mathias, Ringelhan, Marc, Janssen, Klaus-Peter, Nitsche, Ulrich, Garbi, Natalio, Brossart, Peter, Knolle, Percy A., Kurts, Christian, Höchst, Bastian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593699/
https://ncbi.nlm.nih.gov/pubmed/28920004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338995
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