Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis

CD11b(+)Gr1(+) myeloid derived suppressor cells (MDSC) are known to be very potent suppressors of T cell immunity and can be further stratified into granulocytic MDSC and monocytic MDSC in mice based on expression of Ly6G or Ly6C, respectively. Here, using these markers and functional assays, we aim...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Höchst, Bastian, Mikulec, Julita, Baccega, Tania, Metzger, Christina, Welz, Meike, Peusquens, Julia, Tacke, Frank, Knolle, Percy, Kurts, Christian, Diehl, Linda, Ludwig-Portugall, Isis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349817/
https://ncbi.nlm.nih.gov/pubmed/25738302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119662
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