Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination

Tumor immune escape is a critical problem which frequently accounts for the failure of therapeutic tumor vaccines. Among the most potent suppressors of tumor immunity are myeloid derived suppressor cells (MDSCs). MDSCs can be targeted by all-trans-retinoic-acid (atRA), which reduced their numbers an...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Heine, Annkristin, Flores, Chrystel, Gevensleben, Heidrun, Diehl, Linda, Heikenwalder, Mathias, Ringelhan, Marc, Janssen, Klaus-Peter, Nitsche, Ulrich, Garbi, Natalio, Brossart, Peter, Knolle, Percy A., Kurts, Christian, Höchst, Bastian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593699/
https://ncbi.nlm.nih.gov/pubmed/28920004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338995
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