Ubiquitin specific peptidase 4 stabilizes interferon regulatory factor protein and promotes its function to facilitate interleukin-4 expression in T helper type 2 cells

We speculated that ubiquitin specific peptidase 4 (USP4) may deubiquitinate interferon regulatory factor 4 (IRF4) and affect T helper type 2 (Th2) cell function. This study aimed to validate this hypothesis. Here, the interaction between USP4 and IRF4 were analyzed by co-immunoprecipitation assay. T...

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Publicado en:Int J Mol Med
Autores principales: Guo, Zhixiang, Xu, Peng, Ge, Shangqing, Zhang, Chengxin, Zheng, Xiaoyan, Xu, Jinguo, Liu, Zhuang, Li, Bin, Ge, Shenglin
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593473/
https://ncbi.nlm.nih.gov/pubmed/28791349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3087
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