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Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer
Cancers acquire multiple somatic mutations that can lead to the generation of immunogenic mutation-induced neoantigens. These neoantigens can be recognized by the host's immune system. However, continuous stimulation of immune cells against tumor antigens can lead to immune cell exhaustion, whi...
Zapisane w:
| Wydane w: | Cold Spring Harb Mol Case Stud |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593153/ https://ncbi.nlm.nih.gov/pubmed/28619747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a001974 |
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