Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer

Cancers acquire multiple somatic mutations that can lead to the generation of immunogenic mutation-induced neoantigens. These neoantigens can be recognized by the host's immune system. However, continuous stimulation of immune cells against tumor antigens can lead to immune cell exhaustion, whi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Czink, Elena, Kloor, Matthias, Goeppert, Benjamin, Fröhling, Stefan, Uhrig, Sebastian, Weber, Tim F., Meinel, Jörn, Sutter, Christian, Weiss, Karl Heinz, Schirmacher, Peter, Doeberitz, Magnus von Knebel, Jäger, Dirk, Springfeld, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593153/
https://ncbi.nlm.nih.gov/pubmed/28619747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a001974
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados