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Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species

A progressive decline in antioxidant potential and accumulation of reactive oxygen species (ROS) are major causes of pathogenesis of several diseases, including glaucoma. Trabecular meshwork (TM) dysfunction resulting in higher intraocular pressure (IOP) is a hallmark of glaucoma, but its causes are...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Chhunchha, Bhavana, Singh, Prerna, Stamer, W Daniel, Singh, Dhirendra P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592691/
https://ncbi.nlm.nih.gov/pubmed/28904819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.60
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