Načítá se...
Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors
The reversible phosphorylation of proteins controls most cellular functions. Protein kinases have been popular drug targets, unlike phosphatases, which remain a drug discovery challenge. Guanabenz and Sephin1 are selective inhibitors of the phosphatase regulatory subunit PPP1R15A (R15A) that prolong...
Uloženo v:
| Vydáno v: | Nat Struct Mol Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591645/ https://ncbi.nlm.nih.gov/pubmed/28759048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3443 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|