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Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis
The identification of mutations that enhance antibody affinity while maintaining high antibody specificity and stability is a time-consuming and laborious process. Here, we report an efficient methodology for systematically and rapidly enhancing the affinity of antibody variable domains while maximi...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591402/ https://ncbi.nlm.nih.gov/pubmed/28928732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00986 |
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