Therapy-related clonal hematopoiesis in patients with non-hematologic cancers is common and impacts clinical outcome

Clonal hematopoiesis (CH), as evidenced by recurrent somatic mutations in leukemia-associated genes, commonly occurs among aging human hematopoietic stem cells. We analyzed deep coverage, targeted next-generation sequencing (NGS) data of paired tumor and blood samples from 8,810 individuals to asses...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Stem Cell
Autors principals: Coombs, Catherine C., Zehir, Ahmet, Devlin, Sean M., Kishtagari, Ashwin, Syed, Aijazuddin, Jonsson, Philip, Hyman, David M., Solit, David B., Robson, Mark E., Baselga, José, Arcila, Maria E., Ladanyi, Marc, Tallman, Martin S., Levine, Ross L., Berger, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591073/
https://ncbi.nlm.nih.gov/pubmed/28803919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.07.010
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars