Transcription factor RUNX1 regulates platelet PCTP (Phosphatidylcholine transfer protein): Implications for cardiovascular events Differential Effects of RUNX1 variants

BACKGROUND: Phosphatidylcholine Transfer Protein (PCTP) regulates the intermembrane transfer of phosphatidylcholine (PC). Higher platelet PCTP expression is associated with increased platelet responses upon activation of protease-activated receptor 4 (PAR4) thrombin receptors noted in black subjects...

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Publicat a:Circulation
Autors principals: Mao, Guangfen, Songdej, Natthapol, Voora, Deepak, Goldfinger, Lawrence E., Del Carpio-Cano, Fabiola E., Myers, Rachel A., Rao, A. Koneti
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591032/
https://ncbi.nlm.nih.gov/pubmed/28676520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.023711
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