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RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency

Haploinsufficiency of RUNX1 (also known as CBFA2/AML1) is associated with familial thrombocytopenia, platelet dysfunction, and predisposition to acute leukemia. We have reported on a patient with thrombocytopenia and impaired agonist-induced aggregation, secretion, and protein phosphorylation associ...

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Detalhes bibliográficos
Main Authors: Kaur, Gurpreet, Jalagadugula, Gauthami, Mao, Guangfen, Rao, A. Koneti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858475/
https://ncbi.nlm.nih.gov/pubmed/20181616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-214601
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