Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics

Enzyme prodrug therapy (EPT) enables localized conversion of inert prodrugs to active drugs by enzymes. Performance of EPT necessitates that the enzyme remains active throughout the time frame of the envisioned therapeutic application. β-glucuronidase is an enzyme with historically validated perform...

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Detaylı Bibliyografya
Yayımlandı:Adv Healthc Mater
Asıl Yazarlar: Chandrawati, Rona, Olesen, Morten T. J., Marini, Thatiane C. C., Bisra, Gurpal, Guex, Anne Géraldine, de Oliveira, Marcelo G., Zelikin, Alexander N., Stevens, Molly M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590711/
https://ncbi.nlm.nih.gov/pubmed/28699219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201700385
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