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Macroscopic Dynamic Modeling of Sequential Batch Cultures of Hybridoma Cells: An Experimental Validation

Hybridoma cells are commonly grown for the production of monoclonal antibodies (MAb). For monitoring and control purposes of the bioreactors, dynamic models of the cultures are required. However these models are difficult to infer from the usually limited amount of available experimental data and do...

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Bibliographische Detailangaben
Veröffentlicht in:Bioengineering (Basel)
Hauptverfasser: Dewasme, Laurent, Côte, François, Filee, Patrice, Hantson, Anne-Lise, Vande Wouwer, Alain
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590448/
https://ncbi.nlm.nih.gov/pubmed/28952495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering4010017
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