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Prolongation of murine hybridoma cell survival in stationary batch culture by Bcl-xL expression

While the ectopic expression of the anti-apoptoticprotein Bcl-2 has been shown to significantly increaseboth cell viability and antibody production in batchculture, some cell lines are refractory to thesemanipulations. For example, the NS/O and theP3x63Ag8.653 murine myelomas, which express highendo...

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Bibliografiske detaljer
Main Authors: Charbonneau, Joel R., Gauthier, Eric R.
Format: Artigo
Sprog:Inglês
Udgivet: Kluwer Academic Publishers 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449729/
https://ncbi.nlm.nih.gov/pubmed/19003387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008186302600
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