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Macroscopic Dynamic Modeling of Sequential Batch Cultures of Hybridoma Cells: An Experimental Validation

Hybridoma cells are commonly grown for the production of monoclonal antibodies (MAb). For monitoring and control purposes of the bioreactors, dynamic models of the cultures are required. However these models are difficult to infer from the usually limited amount of available experimental data and do...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Dewasme, Laurent, Côte, François, Filee, Patrice, Hantson, Anne-Lise, Vande Wouwer, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590448/
https://ncbi.nlm.nih.gov/pubmed/28952495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering4010017
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