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Visualization of ligand-induced dopamine D(2S) and D(2L) receptor internalization by TIRF microscopy

G protein-coupled receptors (GPCRs), including the dopamine receptors, represent a group of important pharmacological targets. Upon agonist binding, GPCRs frequently undergo internalization, a process that is known to attenuate functional responses upon prolonged exposure to agonists. In this study,...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Tabor, Alina, Möller, Dorothee, Hübner, Harald, Kornhuber, Johannes, Gmeiner, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589927/
https://ncbi.nlm.nih.gov/pubmed/28883522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11436-1
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