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Visualization of ligand-induced dopamine D(2S) and D(2L) receptor internalization by TIRF microscopy
G protein-coupled receptors (GPCRs), including the dopamine receptors, represent a group of important pharmacological targets. Upon agonist binding, GPCRs frequently undergo internalization, a process that is known to attenuate functional responses upon prolonged exposure to agonists. In this study,...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589927/ https://ncbi.nlm.nih.gov/pubmed/28883522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11436-1 |
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