Acute atorvastatin treatment restores the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats

BACKGROUND: Ischemic Postconditioning (IPC) reduces ischemia/reperfusion (I/R) injury under normal conditions. HMG-CoA reductase inhibitors (statins), which inhibit the synthesis of mevalonate, can interfere with the cardioprotective effect of IPC. However, the beneficial role of IPC in hyperlipidem...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Tao, Zhang, Hong-Ju, Krittanawong, Chayakrit, Wang, Su, Tao, Ying, Li, Zhao, Yin, Qiancheng, Zhang, Donghua, Wang, Qian, Huang, Ji, Zhang, Jingmei, Li, Zhizhong, Cheng, Yutong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589651/
https://ncbi.nlm.nih.gov/pubmed/28903412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19232
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