Selective Inhibition of PKCβ2 Restores Ischemic Postconditioning-Mediated Cardioprotection by Modulating Autophagy in Diabetic Rats

Diabetic hearts are more susceptible to myocardial ischemia/reperfusion (I/R) injury and less sensitive to ischemic postconditioning (IPostC), but the underlying mechanisms remain unclear. PKCβ2 is preferentially overactivated in diabetic myocardium, in which autophagy status is abnormal. This study...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Wang, Yafeng, Zhou, Lu, Su, Wating, Huang, Fengnan, Zhang, Yuan, Xia, Zhong-yuan, Xia, Zhengyuan, Lei, Shaoqing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157806/
https://ncbi.nlm.nih.gov/pubmed/32337288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2408240
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