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Acute atorvastatin treatment restores the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats
BACKGROUND: Ischemic Postconditioning (IPC) reduces ischemia/reperfusion (I/R) injury under normal conditions. HMG-CoA reductase inhibitors (statins), which inhibit the synthesis of mevalonate, can interfere with the cardioprotective effect of IPC. However, the beneficial role of IPC in hyperlipidem...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589651/ https://ncbi.nlm.nih.gov/pubmed/28903412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19232 |
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