Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway

Methylglyoxal (MG), an extremely reactive glucose metabolite, exhibits antitumor activity. Glyoxalase I (GLOI), which catalyzes MG metabolism, is associated with the progression of human malignancies. While the roles of MG or GLOI have been demonstrated in some types of cancer, their effects in colo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Chen, Yuan, Fang, Lei, Li, Gefei, Zhang, Jiali, Li, Changxi, Ma, Mengni, Guan, Chen, Bai, Fumao, Lyu, Jianxin, Meng, Qing H.
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2017
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589625/
https://ncbi.nlm.nih.gov/pubmed/28903386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18601
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