Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy

Colorectal cancer (CRC) is prevalent worldwide, and treatment often involves surgery and genotoxic chemotherapy. DNA repair mechanisms, such as base excision repair (BER) and mismatch repair (MMR), may not only influence tumour characteristics and prognosis but also dictate chemotherapy response. De...

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Pubblicato in:Oncotarget
Autori principali: Leguisamo, Natalia M., Gloria, Helena C., Kalil, Antonio N., Martins, Talita V., Azambuja, Daniel B., Meira, Lisiane B., Saffi, Jenifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589573/
https://ncbi.nlm.nih.gov/pubmed/28903334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14909
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