Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy

Colorectal cancer (CRC) is prevalent worldwide, and treatment often involves surgery and genotoxic chemotherapy. DNA repair mechanisms, such as base excision repair (BER) and mismatch repair (MMR), may not only influence tumour characteristics and prognosis but also dictate chemotherapy response. De...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Leguisamo, Natalia M., Gloria, Helena C., Kalil, Antonio N., Martins, Talita V., Azambuja, Daniel B., Meira, Lisiane B., Saffi, Jenifer
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589573/
https://ncbi.nlm.nih.gov/pubmed/28903334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14909
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