Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy

Colorectal cancer (CRC) is prevalent worldwide, and treatment often involves surgery and genotoxic chemotherapy. DNA repair mechanisms, such as base excision repair (BER) and mismatch repair (MMR), may not only influence tumour characteristics and prognosis but also dictate chemotherapy response. De...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Leguisamo, Natalia M., Gloria, Helena C., Kalil, Antonio N., Martins, Talita V., Azambuja, Daniel B., Meira, Lisiane B., Saffi, Jenifer
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589573/
https://ncbi.nlm.nih.gov/pubmed/28903334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14909
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