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MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia

The SET (I2PP2A) oncoprotein is a potent inhibitor of protein phosphatase 2A (PP2A) that regulates many cell processes and important signaling pathways. Despite the importance of SET overexpression and its prognostic impact in both hematologic and solid tumors, little is known about the mechanisms i...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Pippa, Raffaella, Dominguez, Ana, Malumbres, Raquel, Endo, Akinori, Arriazu, Elena, Marcotegui, Nerea, Guruceaga, Elizabeth, Odero, María D.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589557/
https://ncbi.nlm.nih.gov/pubmed/28903318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9840
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