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5′-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure

Oligonucleotide conjugates bearing two pyrene residues attached to 5′-phosphate through a phosphoramide bond were synthesised. Fluorescence spectra of the conjugates show a peak typical of monomer emission (λ(max) 382 nm) and a broad emission peak with λ(max )476 nm, which indicates the excimer form...

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Detalhes bibliográficos
Main Authors: Kostenko, Elena, Dobrikov, Mikhail, Pyshnyi, Dmitrii, Petyuk, Vladislav, Komarova, Nina, Vlassov, Valentin, Zenkova, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55892/
https://ncbi.nlm.nih.gov/pubmed/11522831
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