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New Concepts of Fluorescent Probes for Specific Detection of DNA Sequences: Bis-Modified Oligonucleotides in Excimer and Exciplex Detection

The detection of single base mismatches in DNA is important for diagnostics, treatment of genetic diseases, and identification of single nucleotide polymorphisms. Highly sensitive, specific assays are needed to investigate genetic samples from patients. The use of a simple fluorescent nucleoside ana...

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Main Authors: Gbaj, A, Bichenkova, EV, Walsh, L, Savage, HE, Sardarian, AR, Etchells, LL, Gulati, A, Hawisa, S, Douglas, KT
פורמט: Artigo
שפה:Inglês
יצא לאור: CoAction Publishing 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066750/
https://ncbi.nlm.nih.gov/pubmed/21483539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4176/090801
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