New Concepts of Fluorescent Probes for Specific Detection of DNA Sequences: Bis-Modified Oligonucleotides in Excimer and Exciplex Detection

The detection of single base mismatches in DNA is important for diagnostics, treatment of genetic diseases, and identification of single nucleotide polymorphisms. Highly sensitive, specific assays are needed to investigate genetic samples from patients. The use of a simple fluorescent nucleoside ana...

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Detalhes bibliográficos
Main Authors: Gbaj, A, Bichenkova, EV, Walsh, L, Savage, HE, Sardarian, AR, Etchells, LL, Gulati, A, Hawisa, S, Douglas, KT
Formato: Artigo
Idioma:Inglês
Publicado em: CoAction Publishing 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066750/
https://ncbi.nlm.nih.gov/pubmed/21483539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4176/090801
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