Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer

BACKGROUND: The TMPRSS2-ERG gene fusion is detected in approximately half of primary prostate cancers (PCa) yet the prognostic significance remains unclear. We hypothesized that ERG promotes the expression of common genes in primary PCa and metastatic castration-resistant PCa (CRPC), with the object...

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Publicat a:Prostate
Autors principals: Roudier, Martine P, Winters, Brian R, Coleman, Ilsa, Lam, Hung-Ming, Zhang, Xiaotun, Coleman, Roger, Chéry, Lisly, True, Lawrence D., Higano, Celestia S., Montgomery, Bruce, Lange, Paul H., Snyder, Linda A., Srivistava, Shiv, Corey, Eva, Vessella, Robert L., Nelson, Peter S., Üren, Aykut, Morrissey, Colm
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589183/
https://ncbi.nlm.nih.gov/pubmed/26990456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23171
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