Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer

BACKGROUND: The TMPRSS2-ERG gene fusion is detected in approximately half of primary prostate cancers (PCa) yet the prognostic significance remains unclear. We hypothesized that ERG promotes the expression of common genes in primary PCa and metastatic castration-resistant PCa (CRPC), with the object...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Roudier, Martine P, Winters, Brian R, Coleman, Ilsa, Lam, Hung-Ming, Zhang, Xiaotun, Coleman, Roger, Chéry, Lisly, True, Lawrence D., Higano, Celestia S., Montgomery, Bruce, Lange, Paul H., Snyder, Linda A., Srivistava, Shiv, Corey, Eva, Vessella, Robert L., Nelson, Peter S., Üren, Aykut, Morrissey, Colm
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589183/
https://ncbi.nlm.nih.gov/pubmed/26990456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23171
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