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Physiological/pathological ramifications of transcription factors in the unfolded protein response
Numerous environmental, physiological, and pathological insults disrupt protein-folding homeostasis in the endoplasmic reticulum (ER), referred to as ER stress. Eukaryotic cells evolved a set of intracellular signaling pathways, collectively termed the unfolded protein response (UPR), to maintain a...
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Publicado no: | Genes Dev |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588925/ https://ncbi.nlm.nih.gov/pubmed/28860159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.297374.117 |
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