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The unfolded protein response in immunity and inflammation

The unfolded protein response (UPR) is a highly conserved pathway that allows the cell to manage endoplasmic reticulum (ER) stress that is imposed by the secretory demands associated with environmental forces. In this role, the UPR has increasingly been shown to have crucial functions in immunity an...

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Pubblicato in:Nat Rev Immunol
Autori principali: Grootjans, Joep, Kaser, Arthur, Kaufman, Randal J., Blumberg, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310224/
https://ncbi.nlm.nih.gov/pubmed/27346803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.62
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