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The unfolded protein response in immunity and inflammation

The unfolded protein response (UPR) is a highly conserved pathway that allows the cell to manage endoplasmic reticulum (ER) stress that is imposed by the secretory demands associated with environmental forces. In this role, the UPR has increasingly been shown to have crucial functions in immunity an...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Grootjans, Joep, Kaser, Arthur, Kaufman, Randal J., Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310224/
https://ncbi.nlm.nih.gov/pubmed/27346803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.62
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