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Multifunctional enzymes from reduced genomes - model proteins for simple primordial metabolism?

Billions of years of evolution have yielded today’s complex metabolic networks driven by efficient and highly specialized enzymes. In contrast, the metabolism of the earliest cellular life forms was likely much simpler with only a few enzymes of comparatively low activity. It has been speculated tha...

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Dettagli Bibliografici
Pubblicato in:Mol Microbiol
Autore principale: Seelig, Burckhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588889/
https://ncbi.nlm.nih.gov/pubmed/28665040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13742
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