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Highly Diverse Protein Library Based on the Ubiquitous (β/α)(8) Enzyme Fold Yields Well-Structured Proteins Through In Vitro Folding Selection

Proper protein folding is a prerequisite for protein stability and enzymatic activity. While directed evolution can be a powerful tool to investigate enzymatic function and to isolate novel activities, well-designed libraries of folded proteins are essential. In vitro selection methods are particula...

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Detalhes bibliográficos
Main Authors: Golynskiy, Misha V., Haugner, John C., Seelig, Burckhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896996/
https://ncbi.nlm.nih.gov/pubmed/23956201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300326
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