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Highly Diverse Protein Library Based on the Ubiquitous (β/α)(8) Enzyme Fold Yields Well-Structured Proteins Through In Vitro Folding Selection
Proper protein folding is a prerequisite for protein stability and enzymatic activity. While directed evolution can be a powerful tool to investigate enzymatic function and to isolate novel activities, well-designed libraries of folded proteins are essential. In vitro selection methods are particula...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896996/ https://ncbi.nlm.nih.gov/pubmed/23956201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300326 |
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