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Universal Labeling of 5′-Triphosphate RNAs by Artificial RNA Ligase Enzyme with Broad Substrate Specificity

An artificial RNA ligase specific to RNA with a 5′-triphosphate (PPP-RNA) exhibits broad sequence specificity on model substrates and secondary siRNAs with direct applications in the identification of PPP-RNAs through sequencing.

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Detalles Bibliográficos
Autores principales: Haugner, John C., Seelig, Burckhard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838195/
https://ncbi.nlm.nih.gov/pubmed/23851643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc44454f
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