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Machine learning reveals a non‐canonical mode of peptide binding to MHC class II molecules
MHC class II molecules play a fundamental role in the cellular immune system: they load short peptide fragments derived from extracellular proteins and present them on the cell surface. It is currently thought that the peptide binds lying more or less flat in the MHC groove, with a fixed distance of...
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Publicado no: | Immunology |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588850/ https://ncbi.nlm.nih.gov/pubmed/28542831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12763 |
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