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Machine learning reveals a non‐canonical mode of peptide binding to MHC class II molecules

MHC class II molecules play a fundamental role in the cellular immune system: they load short peptide fragments derived from extracellular proteins and present them on the cell surface. It is currently thought that the peptide binds lying more or less flat in the MHC groove, with a fixed distance of...

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Foilsithe in:Immunology
Main Authors: Andreatta, Massimo, Jurtz, Vanessa I., Kaever, Thomas, Sette, Alessandro, Peters, Bjoern, Nielsen, Morten
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588850/
https://ncbi.nlm.nih.gov/pubmed/28542831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12763
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