Limitations of Ab Initio Predictions of Peptide Binding to MHC Class II Molecules

Successful predictions of peptide MHC binding typically require a large set of binding data for the specific MHC molecule that is examined. Structure based prediction methods promise to circumvent this requirement by evaluating the physical contacts a peptide can make with an MHC molecule based on t...

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Autores principales: Zhang, Hao, Wang, Peng, Papangelopoulos, Nikitas, Xu, Ying, Sette, Alessandro, Bourne, Philip E., Lund, Ole, Ponomarenko, Julia, Nielsen, Morten, Peters, Bjoern
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822856/
https://ncbi.nlm.nih.gov/pubmed/20174654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009272
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