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Membrane‐bound Dickkopf‐1 in Foxp3(+) regulatory T cells suppresses T‐cell‐mediated autoimmune colitis
Induction of tolerance is a key mechanism to maintain or to restore immunological homeostasis. Here we show that Foxp3(+) regulatory T (Treg) cells use Dickkopf‐1 (DKK‐1) to regulate T‐cell‐mediated tolerance in the T‐cell‐mediated autoimmune colitis model. Treg cells from DKK‐1 hypomorphic doubleri...
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| Publicado no: | Immunology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588763/ https://ncbi.nlm.nih.gov/pubmed/28556921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12766 |
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