Statistical classifiers for diagnosing disease from immune repertoires: a case study using multiple sclerosis

BACKGROUND: Deep sequencing of lymphocyte receptor repertoires has made it possible to comprehensively profile the clonal composition of lymphocyte populations. This opens the door for novel approaches to diagnose and prognosticate diseases with a driving immune component by identifying repertoire s...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Ostmeyer, Jared, Christley, Scott, Rounds, William H., Toby, Inimary, Greenberg, Benjamin M., Monson, Nancy L., Cowell, Lindsay G.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588725/
https://ncbi.nlm.nih.gov/pubmed/28882107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1814-6
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