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Statistical classifiers for diagnosing disease from immune repertoires: a case study using multiple sclerosis

BACKGROUND: Deep sequencing of lymphocyte receptor repertoires has made it possible to comprehensively profile the clonal composition of lymphocyte populations. This opens the door for novel approaches to diagnose and prognosticate diseases with a driving immune component by identifying repertoire s...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Ostmeyer, Jared, Christley, Scott, Rounds, William H., Toby, Inimary, Greenberg, Benjamin M., Monson, Nancy L., Cowell, Lindsay G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588725/
https://ncbi.nlm.nih.gov/pubmed/28882107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1814-6
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