Statistical classifiers for diagnosing disease from immune repertoires: a case study using multiple sclerosis

BACKGROUND: Deep sequencing of lymphocyte receptor repertoires has made it possible to comprehensively profile the clonal composition of lymphocyte populations. This opens the door for novel approaches to diagnose and prognosticate diseases with a driving immune component by identifying repertoire s...

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Foilsithe in:BMC Bioinformatics
Main Authors: Ostmeyer, Jared, Christley, Scott, Rounds, William H., Toby, Inimary, Greenberg, Benjamin M., Monson, Nancy L., Cowell, Lindsay G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588725/
https://ncbi.nlm.nih.gov/pubmed/28882107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1814-6
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