Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu

BACKGROUND: In conditions of immunosuppression, the central nervous sty 5ystem (CNS) is the main target tissue for the reactivation of infection by Trypanosoma cruzi, the causative agent of Chagas disease. In experimental T. cruzi infection, interferon gamma (IFNγ)(+) microglial cells surround astro...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Silva, Andrea Alice, Silva, Rafael Rodrigues, Gibaldi, Daniel, Mariante, Rafael Meyer, dos Santos, Jessica Brandão, Pereira, Isabela Resende, Moreira, Otacílio Cruz, Lannes-Vieira, Joseli
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588596/
https://ncbi.nlm.nih.gov/pubmed/28877735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0952-0
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki