CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy

CCL3, a member of the CC-chemokine family, has been associated with macrophage recruitment to heart tissue and parasite control in the acute infection of mouse with Trypanosoma cruzi, the causative agent of Chagas disease. Here, we approached the participation of CCL3 in chronic chagasic cardiomyopa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gibaldi, Daniel, Vilar-Pereira, Glaucia, Pereira, Isabela Resende, Silva, Andrea Alice, Barrios, Leda Castaño, Ramos, Isalira Peroba, Mata dos Santos, Hílton Antônio, Gazzinelli, Ricardo, Lannes-Vieira, Joseli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063958/
https://ncbi.nlm.nih.gov/pubmed/32194558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00306
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