Overexpression of REIC/Dkk-3 suppresses the expression of CD147 and inhibits the proliferation of human bladder cancer cells

Our group previously developed an adenoviral vector encoding the REIC/Dkk-3 gene (Ad-REIC), a tumor suppressor, for cancer gene therapy. The Ad-REIC agent induces apoptosis and inhibits invasion in a number of cancer cell lines; however, the molecular mechanisms underlying its effects remain unclear...

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Publicado en:Oncol Lett
Autores principales: Horikawa, Yuhei, Watanabe, Masami, Sadahira, Takuya, Ariyoshi, Yuichi, Kobayashi, Yasuyuki, Araki, Motoo, Wada, Koichiro, Ochiai, Kazuhiko, Li, Shun-Ai, Nasu, Yasutomo
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588074/
https://ncbi.nlm.nih.gov/pubmed/28927069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6548
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