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A systematic comparison of error correction enzymes by next-generation sequencing

Gene synthesis, the process of assembling gene-length fragments from shorter groups of oligonucleotides (oligos), is becoming an increasingly important tool in molecular and synthetic biology. The length, quality and cost of gene synthesis are limited by errors produced during oligo synthesis and su...

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Publicat a:Nucleic Acids Res
Autors principals: Lubock, Nathan B., Zhang, Di, Sidore, Angus M., Church, George M., Kosuri, Sriram
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587813/
https://ncbi.nlm.nih.gov/pubmed/28911123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx691
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