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CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level

The methylcytosine-binding domain 2 (MBD2) protein recruits the nucleosome remodeling and deacetylase complex (NuRD) to methylated DNA to modify chromatin and regulate transcription. Importantly, MBD2 functions within CpG islands that contain 100s to 1000s of potential binding sites. Since NuRD phys...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Pan, Hai, Bilinovich, Stephanie M., Kaur, Parminder, Riehn, Robert, Wang, Hong, Williams, David C.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587734/
https://ncbi.nlm.nih.gov/pubmed/28637186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx548
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