تحميل...

5-Halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2)

Perturbations in cytosine methylation signals are observed in the majority of human tumors; however, it is as yet unknown how methylation patterns become altered. Epigenetic changes can result in the activation of transforming genes as well as in the silencing of tumor suppressor genes. We report th...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Valinluck, Victoria, Liu, Pingfang, Kang, Joseph I., Burdzy, Artur, Sowers, Lawrence C.
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2005
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140371/
https://ncbi.nlm.nih.gov/pubmed/15917437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki612
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